MSM specifically inhibits the activity of a chemical called NF-kB, which plays a key role in regulating the immune response to infection and is linked to inflammatory disease. In some studies, MSM has demonstrated its capabilities at protecting cartilage from degeneration, which is the driving force of osteoarthritis.
Sulphur is one of the major building blocks of glycosaminoglycans — key structural components in cartilage. MSM may also have a role to play in suppressing the overactivity of inflammatory compounds that can trigger allergic reactions.
Pre-treatment with MSM has shown to reduce muscle soreness following strenuous resistance and endurance exercise. A study of 16 unfit men revealed that taking MSM could reduce the signs of oxidative stress on their bodies after exercise, helping to protect against damage caused by free radicals.
Meanwhile, a study of 22 runners found that taking 3g of MSM for three weeks before a half marathon and two days afterwards, reduced post-race muscle and joint pain. Italian researchers discovered that a cream containing a combination of MSM and milk thistle applied to the skin could reduce symptoms of rosacea.
This may be because MSM is source of sulphur, and sulphur has antibacterial properties that have been shown to tackle mild acne. Applying MSM topically to the skin to reduce visible signs of ageing has shown some promise in early studies. A fortnightly peeling session incorporating MSM helped reduced pigmentation of melisma, skin elasticity, and the degree of wrinkling in people affected by sun damage and other age-related skin markers. However, this study also involved the application of Pyruvic acid, a potent chemical peeling agent, which the positive outcomes of the study could be attributed to.
Having said that, in the skincare world there is increasing anecdotal evidence that applying MSM can leave skin feeling softer and smoother. Another study concluded that taking an oral MSM supplement helped reduce fine lines and wrinkles over 16 weeks.
The group receiving the supplement also reported improved overall quality of life and less difficulty walking and getting out of bed 2.
Another study in 32 people with lower back pain found that taking a glucosamine supplement containing MSM significantly reduced lumbar stiffness and pain upon movement, plus greatly increased quality of life 3.
Studies have shown that MSM is effective in reducing joint pain, stiffness and swelling. In doing so, it can improve your quality of life. Additionally, MSM can increase levels of glutathione, a potent antioxidant produced by your body. Another study in 40 physically active men showed that taking 3 grams of MSM before exhaustive exercise decreased the release of inflammatory cytokines and prevented the over-stress of immune cells, compared to a placebo 7.
During exhaustive exercise, muscle damage occurs and oxidative stress increases 8. This causes athletes to experience muscle soreness and pain, which can hinder athletic performance and training. MSM can naturally speed muscle recovery after intense exercise by reducing inflammation and oxidative stress. A study in 18 men showed that taking 50 mg of MSM powder per kg of body weight for 10 days significantly reduced exercise-induced muscle damage and increased antioxidant activity following an 8.
In one study, 22 healthy women received 3 grams of MSM or a placebo per day for three weeks leading up to a half marathon. The MSM group reported less muscle soreness and joint pain than the placebo group Another study found that athletic men taking 3 grams of MSM daily for two weeks had lower levels of IL-6 and less muscle pain after intense resistance exercise MSM may help reduce pain, muscle damage and oxidative stress after intense exercise, helping you recover more quickly.
Arthritis is a common inflammatory condition that causes pain, stiffness and a reduced range of motion in your joints. A study in 49 people with knee osteoarthritis found that taking 3. Additionally, it can enhance the effectiveness of other common supplements used to treat arthritis such as glucosamine sulfate, chondroitin sulfate and boswellic acid. One study found that combining MSM with glucosamine and chondroitin was more effective at decreasing pain and stiffness in people with knee osteoarthritis than glucosamine and chondroitin alone Another study showed that a daily supplement containing 5 grams of MSM and 7 grams of boswellic acid was more effective than glucosamine at reducing pain and improving function in people with knee osteoarthritis MSM supplements have been shown to help reduce pain and stiffness in people with arthritis.
They may also help improve physical function. Allergic rhinitis is an allergic reaction that causes symptoms such as watery eyes, sneezing, itching, runny nose and nasal congestion After exposure to an allergen, many inflammatory substances such as prostaglandins and cytokines are released, which leads to unpleasant symptoms. It may decrease allergic reactions by lowering inflammation and inhibiting the release of cytokines and prostaglandins A study in 50 people with allergic rhinitis found that a dose of 2, mg of MSM per day over 30 days reduced symptoms including itching, congestion, shortness of breath, sneezing and coughing Additionally, participants experienced a significant increase in energy by day 14 If you are looking to increase hair growth or treat hair loss, traditional treatment methods are recommended.
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At dosages up to four grams per day, the supplement is well tolerated by most people. It's few known side effects are typically mild. It's not hard to get MSM via your diet. MSM is naturally found in:. This doesn't necessarily mean you're getting a lot through your diet, though. As foods are processed, MSM is destroyed. You may be able to increase the amount you get in food by concentrating on fresh whole foods.
DMSO is available in an industrial grade and a medical-grade. DMSO was touted as a miracle treatment for arthritis in the s but became controversial because of potential problems and unpleasant side effects.
MSM is primarily sold over-the-counter as an oral formulation solution, tablets, or capsules. It is sometimes combined with other dietary supplements, such as:. Some multi-ingredient joint formulas include many other supplements, as well. MSM is also available as a topical cream. MSM not only reduces inflammation, but it also protects your cartilage from degradation, such as that seen in osteoarthritis, by suppressing interleukin 1-beta IL-1b and tumor necrosis factor-alpha TNF-a , according to a review of literature published in The result of lowered inflammation and cartilage preservation is an improved range of motion and physical function.
MSM can also reduce exercise-related muscle damage, especially when taken before strenuous resistance or endurance exercises, the review states.
This is believed to be due to its antioxidant effects. MSM may increase your sensitivity to alcohol, according to anecdotal evidence. Some other sulfur-containing molecules are used to combat alcoholism due to severe side effects from the combination. However, researchers haven't yet specifically explored MSM's relationship with alcohol. Until more is known, it's best to be cautious with alcohol while you're taking MSM.
Be sure to inform your healthcare provider that you are going to take MSM. Interactions between MSM and other prescription medications, non-prescription medications, dietary supplements, or herbal remedies are possible but unknown. If you are going to buy MSM, it is important to buy from a reputable manufacturer or vendor.
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